2 edition of Translational Control found in the catalog.
by Cold Spring Harbor Laboratory Press
Written in English
|The Physical Object|
Start studying Translational Control. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Shop the Black Friday Sale: Get 50% off Quizlet Plus through Monday Learn more. translation procedures. He writes that, "[w]hile translation methods relate to whole texts, translation procedures are used for sentences and the smaller units of language" (p). He goes on to refer to the following methods of translation: • Word-for-word translation: in which the SL word order is .
fates. Translational control of key mRNAs spatially organizes cell signaling pathways, localizes transcription factor activities, and controls germ cell precursor development. From the few mRNAs studied thus far, some themes are beginning to emerge. Control of maternal mRNA translation begins in the hermaphrodite germ line. This book provides a premier resource to a wide audience, whether it be the general reader seeking a broad view of the field, a clinician interested in the role of protein translation in human disease, the bench researcher looking for state-of-the-art technologies, or computational scientists involved in cutting edge molecular modeling.
Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression: International Conference Proceedings (Developments in biochemistry) - Kindle edition by Grunberg-Manago, Marianne. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Interaction of Translational Manufacturer: Elsevier. Offered by University of Rochester. Translational science seeks to speed up the process of moving research discoveries from the laboratory into healthcare practices. Numerous scientific and organizational roadblocks can act as obstacles along the path of translation and ultimately hinder the speed of progress in medical research. The National Center for Advancing Translational Sciences (NCATS.
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The control of gene expression can also utilize translational mechanisms. These mechanisms are usually directed at initiation.
For example, in response to virus challenge, the protein interferon is released and turns off protein synthesis in neighboring cells by a dual mechanism. First, interferon induces mRNA degradation. In addition, as the title indicates, this edition has a new focus on the role of translational control in human development and disease.
This book, with 30 chapters written by experts in the field, is essential reading for anyone interested in the process of translation, its regulation, and how its failure can Translational Control book the cause of disease.5/5(1).
Since the publication of Translational Control, there has been fresh interest in protein synthesis and recognition of the key role of translation control mechanisms in regulating gene expression.
This new monograph updates and expands the scope of the earlier book but it also takes a fresh look at the field. In a new format, the first eight chapters provide broad overviews, while each of 4/5(1).
Click to Enlarge. Translational Control in Biology and Medicine (Cold Spring Harbor Monograph Series 48) Book Series: Cold Spring Harbor Monograph Series Subject Area(s): Molecular Biology; Biochemistry Edited by Michael B.
Mathews, UMDNJ-New Jersey Medical School, Newark, New Jersey; Nahum Sonenberg, McGill University, Montreal, Canada; John W.B. Hershey, University of California. Translational biology in medicine is a scientific process of bridge building between observations in the basic biological sciences and their application in the medical sciences.
This chapter introduces the concept of translational medicine and emphasizes a role for model biological systems used in translational medicine to explore molecular.
Translational regulation refers to the control of the levels of protein synthesized from its regulation is vastly important to the cellular response to stressors, growth cues, and comparison to transcriptional regulation, it results in much more immediate cellular adjustment through direct regulation of protein concentration.
Translational control plays an essential role in the regulation of gene expression. It is especially important in defining the proteome, maintaining homeostasis, and controlling cell proliferation, growth, and development. Numerous disease states result from aberrant regulation of protein synthesis, so understanding the molecular basis and.
The central concept of translational control is that gene expression can be regulated by the efficiency of utilization of mRNA in specifying protein synthesis. Each phase of translation can be under the control of a number of physiological and pathological influences, however, the majority of known control mechanisms target the initiation phase.
Control of RNA expression by cytoplasmic localization. Not only is the time of mRNA translation regulated, but so is the place of RNA expression. Just like the selective repression of mRNA translation, the selective localization of messages is also often accomplished through their 3´ UTRs, and it is also often performed in oocytes.
Translational control in metabolic diseases: the role of mTOR signaling in obesity and diabetes / S.C. Kozma, S.H. Um and G. Thomas. Translational control of synaptic plasiticity and learning and memory / E. Klann and J.D. Richter Translational control in development / B.
Thompson, M. Wickens and J. Kimble UN Environment LAC office is looking for a UN Online Volunteer who will collaborate with the translation from English to Spanish of a guide book ( pages = 42, words) regarding legal themes connected to the options to control Hydroflourocarbons within the implementation of the Montreal Protocol.
In addition, as the title indicates, this edition has a new focus on the role of translational control in human development and disease. This book, with 30 chapters written by experts in the field, is essential reading for anyone interested in the process of translation, its regulation, and how its failure can be the cause of : $ Genre/Form: Congress Congresses Conference papers and proceedings: Additional Physical Format: Online version: Translational control.
Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory, References: Gebauer F, Hentze MW () Molecular mechanisms of translational control. Nat. Rev. Mol. Cell Biol. 5(10), – Steitz TA () A structural understanding of the dynamic ribosome machine. Nat. Rev. Mol. Cell Biol. 9(3), – Sonenberg N, Hinnebusch AG () Regulation of translation initiation in eukaryotes: mechanisms and biological targets.
Principles of Translational Control John W.B. Hershey,1 Nahum Sonenberg,2 and Michael B. Mathews3 1Department of Biochemistry and Molecular Medicine, University of California, Davis, California 2Goodman Cancer Research Centre and Department of Biochemistry, McGill University, Montreal, Quebec H3A 1A3, Canada 3Department of Medicine, Rutgers New Jersey Medical School, Newark.
This book, with 30 chapters written by experts in the field, is essential reading for anyone interested in the process of translation, its regulation, and how its failure can be the cause of disease.
Translational Control of Synaptic Plasticity and Learning and Memory Translational Control in Development Selected Reviews: Dever TE, Green R () The elongation, termination, and recycling phases of translation in eukaryotes.
Cold Spring Harb Perspect Biol 4(7), a; Gebauer F, Hentze MW () Molecular mechanisms of translational control. Nat. Rev. Mol. Cell Biol. 5(10), – Hinnebusch AG () Molecular mechanism of scanning and start codon selection in eukaryotes. Control of gene expression in eukaryotic cells occurs at which level(s).
only the transcriptional level b. epigenetic and transcriptional levels c. epigenetic, transcriptional, and translational levels d.
epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels. Translational control of key mRNAs spatially organizes cell signaling pathways, localizes transcription factor activities, and controls germ cell precursor development.
From the few mRNAs studied thus far, some themes are beginning to emerge. Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology and translational science.
It contains contributions from leaders in their fields and abundant references. This volume focuses on translational control in health and : Elsevier Science.
Translational control in the endoplasmic reticulum stress response. J. Clin. Invest. – [PMC free article] Ross E.M., Wilkie T.M. GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Annu.Control of this process is largely dependent on the RNA molecule.
As previously discussed, the stability of the RNA will have a large impact on its translation into a protein. As the stability changes, the amount of time that it is available for translation also changes. The Initiation Complex and Translation Rate.Key Terms.
targeted therapy: a type of medication that blocks the growth of cancer cells by interfering with specific targeted molecules rather than by interfering with rapidly dividing cells; cancer: a disease in which the cells of a tissue undergo uncontrolled (and often rapid) proliferation; post-translational modification: the chemical modification of a protein after its translation; one.